Endocrine Abstracts

Introduction: Obesity has been associated with a low-level activation of the acute-phase response. The aim of the present study was to compare inflammatory parameters in patients with obesity and a control group, and to evaluate the effect of weight loss on these parameters.Methods: Sixty-seven severe or morbid obese patients (51 women, 16 men), aged 34±11 years, were compared with 67 normal-weight controls (45 women, 22 men), aged 32±10 years....

Introduction: Several haemostatic disturbances have been described in obese patients. Nevertheless, the state of coagulation inhibitors has been scarcely studied in these patients. Activated protein C (APC) is the anticoagulant enzyme formed upon activation of the protein C (PC) by the thrombin-thrombomodulin complex on the surface of endothelial cells. Morbid obesity is associated to endothelial dysfunction, which could cause a reduction in APC generation.<p class="abstex...

Morbid obesity is associated with a decreased life expectancy and a myriad of serious medical problems. The Roux-en-Y gastric bypass (RYGBP) is the most effective procedure for the treatment of these patients, but it can be responsible of early and late complications. The aim of this prospective study was to evaluate the rate of visceral protein malnutrition (VPM) in morbid obese (MO) patients two years after laparoscopic RYGBP. Albumin (Alb), prealbumin (Prealb), transferrin ...